Ijprbs 210

نویسندگان

  • Rashmi Sisodia
  • GARIMA SHARMA
  • RASHMI SISODIA
چکیده

The present study focused on the possible protective effect of Prunus domestica extract (PDE) against radiation induced damage in liver and small intestine of Swiss albino distributed into five groups of 10 mice each. fruits extract (PDE) was evaluated for in vivo activity against whole body gamma irradiation in Radiation induced histological lesions and antioxidant parameters were observed. PDE was found to have strong radical scaven activity in 2, 2diphenyl-1-picrylhydrazyl (DPPH supplementation augmented the antioxidant defence indices, such as reduced glutathione (GSH), superoxide dismutase (SOD) and catalase (CAT) lowered by radiation exposure. Histopathological observations revealed damage in irradiated animals which were found to be reduced by supplementation of PDE prior/post irradiation. These findings suggest the possible radio protective role of antioxidants present in PDE in ameliorating hepatic and intestinal injury via free radical scavenging mechanism. ISSN: 2277-8713 IJPRBS mice. Male mice were

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تاریخ انتشار 2012